Molecular Mechanisms of Protein–Lipid Interactions and Protein Folding of Heterogeneous Amylin and Tau Oligomers on Lipid Nanodomains That Link to Alzheimer’s

The disruption of cell membranes by tau and amylin oligomers is linked to amyloid diseases such as Alzheimer’s and diabetes, respectively. The recent studies suggest that misfolded tau and amylin can form neurotoxic hetero-oligomers that are structurally different from homo-oligomers. However, the m...

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Bibliographic Details
Main Authors: Natalia Santos, Luthary Segura, Amber Lewis, Thuong Pham, Kwan H. Cheng
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Macromol
Subjects:
Online Access:https://www.mdpi.com/2673-6209/3/4/46