Altered FGF Signaling Pathways Impair Cell Proliferation and Elevation of Palate Shelves.

Altered FGF Signaling Pathways Impair Cell Proliferation and Elevation of Palate Shelves.

In palatogenesis, palatal shelves are patterned along the mediolateral axis as well as the anteroposterior axis before the onset of palatal fusion. Fgf10 specifically expressed in lateral mesenchyme of palate maintains Shh transcription in lateral epithelium, while Fgf7 activated in medial mesenchym...

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Bibliographic Details
Main Authors: Weijie Wu, Shuping Gu, Cheng Sun, Wei He, Xiaohua Xie, Xihai Li, Wenduo Ye, Chunlin Qin, Yiping Chen, Jing Xiao, Chao Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4558018?pdf=render

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http://europepmc.org/articles/PMC4558018?pdf=render

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