An in vitro model of skeletal muscle volume regulation.

Hypertonic media causes cells to shrink due to water loss through aquaporin channels. After acute shrinkage, cells either regulate their volume or, alternatively, undergo a number of metabolic changes which ultimately lead to cell death. In many cell types, hypertonic shrinkage is followed by apopto...

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Bibliographic Details
Main Authors: Anna Wibberley, Caroline A Staunton, Claire H Feetham, Alexey A Vereninov, Richard Barrett-Jolley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4452315?pdf=render