Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues

Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues

Malaria is among the tropical diseases that cause the most deaths in Africa. Around 500,000 malaria deaths are reported yearly among African children under the age of five. Chloroquine (CQ) is a low-cost antimalarial used worldwide for the treatment of Plasmodium vivax malaria. Due to resistance mec...

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Bibliographic Details
Main Authors: Wilian A. Cortopassi, Emma Gunderson, Yasmin Annunciato, Antony.E.S. Silva, Amália dos Santos Ferreira, Carolina Bioni Garcia Teles, Andre S. Pimentel, Roopa Ramamoorthi, Marcos L Gazarini, Mario R. Meneghetti, Rafael.V.C. Guido, Dhelio B. Pereira, Matthew P. Jacobson, Antoniana U. Krettli, Anna Caroline C Aguiar
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Malaria
Chloroquine
Resistance
ACTs
DAQ
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320722000240

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http://www.sciencedirect.com/science/article/pii/S2211320722000240

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