The Role of the Endothelium in HPS Pathogenesis and Potential Therapeutic Approaches

American hantaviruses cause a highly lethal acute pulmonary edema termed hantavirus pulmonary syndrome (HPS). Hantaviruses nonlytically infect endothelial cells and cause dramatic changes in barrier functions of the endothelium without disrupting the endothelium. Instead hantaviruses cause changes i...

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Bibliographic Details
Main Authors: Irina Gavrilovskaya, Elena Gorbunova, Valery Matthys, Nadine Dalrymple, Erich Mackow
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Advances in Virology
Online Access:http://dx.doi.org/10.1155/2012/467059