Short-term effects of etifoxine on human gut microbiome in healthy men

Short-term effects of etifoxine on human gut microbiome in healthy men

BackgroundNeurosteroids have recently gained in interest as a treatment strategy for affective disorders. Etifoxine is known for its dual mode of action, one of which is to stimulate endogenous neurosteroid synthesis. The gut microbiome has been studied in affective disorders, but it has not been in...

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Bibliographic Details
Main Authors: André Manook, Thomas C. Baghai, Marco Riebel, Caroline Nothdurfter, Jens Volkmar Schwarzbach, André Gessner, Rainer Rupprecht, Andreas Hiergeist
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Neuroscience
Subjects:
gut microbiome
etifoxine
neurosteroids
GABA-A transmission
Williams design
16S rRNA amplicon sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1188847/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1188847/full

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