Exosomes derived from heat shock preconditioned bone marrow mesenchymal stem cells alleviate cisplatin-induced ototoxicity in mice

Exosomes derived from heat shock preconditioned bone marrow mesenchymal stem cells alleviate cisplatin-induced ototoxicity in mice

Abstract NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome contributes to the development of cisplatin-induced ototoxicity. Whether heat shock pretreatment could be utilized to up-regulate 70 kilodalton heat shock proteins (HSP70) expression in bone marrow mesenchymal stem cell...

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Bibliographic Details
Main Authors: Tao Yang, Wei Li, Anquan Peng, Qin Wang
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Journal of Biological Engineering
Subjects:
Bone marrow mesenchymal stem cells
Exosomes
Heat shock precondition
Cisplatin-induced ototoxicity
Online Access:https://doi.org/10.1186/s13036-022-00304-w

Internet

https://doi.org/10.1186/s13036-022-00304-w

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