A New Baroreceptor Sensitivity-Restoring Ca-Channel Blocker Diminishes Age-Related Morning Blood Pressure Increase in Hypertensive Patients: Open-Label Monitoring of Azelnidipine Treatment for Hypertension in the Early Morning (At-HOME) Study

Background: Morning blood pressure (BP) surge, which exhibits an age-related increase, is a risk factor for stroke in elderly hypertensive patients, independently of the 24-h BP level. We studied the effect of the new baroreceptor sensitivity (BRS)-restoring Ca-channel blocker (CCB) azelnidipine (AZ...

Full description

Bibliographic Details
Main Authors: Mitsunori Sugiyama, Kazuyuki Shimada, Kazuhito Shiosakai, Katsutoshi Hiramatsu, Masayuki Shirayama, Kazuomi Kario
Format: Article
Language:English
Published: MDPI AG 2010-01-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/3/1/225/