Integrated metagenomics/metaproteomics reveals human host-microbiota signatures of Crohn's disease.

Crohn's disease (CD) is an inflammatory bowel disease of complex etiology, although dysbiosis of the gut microbiota has been implicated in chronic immune-mediated inflammation associated with CD. Here we combined shotgun metagenomic and metaproteomic approaches to identify potential functional...

Full description

Bibliographic Details
Main Authors: Alison R Erickson, Brandi L Cantarel, Regina Lamendella, Youssef Darzi, Emmanuel F Mongodin, Chongle Pan, Manesh Shah, Jonas Halfvarson, Curt Tysk, Bernard Henrissat, Jeroen Raes, Nathan C Verberkmoes, Claire M Fraser, Robert L Hettich, Janet K Jansson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23209564/pdf/?tool=EBI