A rat model of cirrhosis with well-differentiated hepatocellular carcinoma induced by thioacetamide

A rat model of cirrhosis with well-differentiated hepatocellular carcinoma induced by thioacetamide

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths, and commonly associated with hepatic fibrosis or cirrhosis. This study aims to establish a rat model mimicking the progression from liver fibrosis to cirrhosis and subsequently to HCC using thioacetamide (TAA). We utilized m...

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Bibliographic Details
Main Authors: Zhiping Hu, Takeshi Kurihara, Yiyue Sun, Zeliha Cetin, Rodrigo M. Florentino, Lanuza A. P. Faccioli, Zhenghao Liu, Bo Yang, Alina Ostrowska, Joseph D. Locker, Alejandro Soto-Gutierrez, Evan R. Delgado
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Gastroenterology
Subjects:
thioacetamide
cholangiocarcinoma (CCA)
hepatocellular carcinoma
fibrosis
cirrhosis
mixed phenotype
Online Access:https://www.frontiersin.org/articles/10.3389/fgstr.2024.1427820/full

Internet

https://www.frontiersin.org/articles/10.3389/fgstr.2024.1427820/full

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