Endothelial-Derived APT1-Mediated Macrophage-Endothelial Cell Interactions Participate in the Development of Atherosclerosis by Regulating the Ras/MAPK Signaling Pathway

Acyl-protein thioesterase 1 (APT1) can affect H-Ras localization and function by promoting its depalmitoylation. However, relatively little attention has been paid to the effects of APT1 on H-Ras in the cardiovascular system. In this study, we revealed its roles in atherosclerosis development using...

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Bibliographic Details
Main Authors: Xinghua Wang, Lijun Cheng, Huaying Fu, Calista Zhuo Yi Chan, Gary Tse, Tong Liu, Guangping Li
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/4/551