Improved 2,3-Butanediol Production Rate of Metabolically Engineered <i>Saccharomyces cerevisiae</i> by Deletion of <i>RIM15</i> and Activation of Pyruvate Consumption Pathway

Improved 2,3-Butanediol Production Rate of Metabolically Engineered <i>Saccharomyces cerevisiae</i> by Deletion of <i>RIM15</i> and Activation of Pyruvate Consumption Pathway

<i>Saccharomyces cerevisiae</i> is a promising host for the bioproduction of higher alcohols, such as 2,3-butanediol (2,3-BDO). Metabolically engineered <i>S. cerevisiae</i> strains that produce 2,3-BDO via glycolysis have been constructed. However, the specific 2,3-BDO produ...

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Bibliographic Details
Main Authors: Masahiko Sugimura, Taisuke Seike, Nobuyuki Okahashi, Yoshihiro Izumi, Takeshi Bamba, Jun Ishii, Fumio Matsuda
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Saccharomyces cerevisiae</i>
2,3-butanediol
<i>RIM15</i>
metabolome analysis
Gibbs free energy change
metabolic engineering
Online Access:https://www.mdpi.com/1422-0067/24/22/16378

Internet

https://www.mdpi.com/1422-0067/24/22/16378

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