Chronic carbon disulfide exposure induces parkinsonian pathology via α-synuclein aggregation and necrosome complex interaction

Summary: Exposure to carbon disulfide (CS2) has been associated with an increased incidence of parkinsonism in workers, but the mechanism underlying this association remains unclear. Using a rat model, we investigated the effects of chronic CS2 exposure on parkinsonian pathology. Our results showed...

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Bibliographic Details
Main Authors: Zhidan Liu, Kang Kang, Shulin Shan, Shuai Wang, Xianjie Li, Hui Yong, Zhengcheng Huang, Yiyu Yang, Zhaoxiong Liu, Yanan Sun, Yao Bai, Fuyong Song
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223018643