Comparative genomics of Acinetobacter baumannii and therapeutic bacteriophages from a patient undergoing phage therapy

A patient with a multidrug-resistant bacterial infection was successfully treated in 2016 using phage therapy. Here, the authors sequence the genomes of the therapeutic phages and three bacterial strains isolated before and during treatment, and show that the same mutations conferring phage resistan...

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Bibliographic Details
Main Authors: Mei Liu, Adriana Hernandez-Morales, James Clark, Tram Le, Biswajit Biswas, Kimberly A. Bishop-Lilly, Matthew Henry, Javier Quinones, Logan J. Voegtly, Regina Z. Cer, Theron Hamilton, Robert T. Schooley, Scott Salka, Ry Young, Jason J. Gill
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31455-5