Identification of a Hypomorphic <i>FANCG</i> Variant in Bernese Mountain Dogs

Identification of a Hypomorphic <i>FANCG</i> Variant in Bernese Mountain Dogs

Bernese mountain dogs (BMDs), have an overall cancer incidence of 50%, half of which is comprised of an otherwise rare tumor, histiocytic sarcoma (HS). While recent studies have identified driver mutations in the MAPK pathway, identification of key predisposing genes has been elusive. Studies have i...

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Bibliographic Details
Main Authors: Katheryn Meek, Ya-Ting Yang, Marilia Takada, Maciej Parys, Marlee Richter, Alexander I. Engleberg, Tuddow Thaiwong, Rachel L. Griffin, Peter Z. Schall, Alana J. Kramer, Vilma Yuzbasiyan-Gurkan
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Genes
Subjects:
Bernese mountain dog
histiocytic sarcoma
fanconi anemia
cancer
comparative genetics
Online Access:https://www.mdpi.com/2073-4425/13/10/1693

Internet

https://www.mdpi.com/2073-4425/13/10/1693

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