Targeting fatty acid synthase reduces aortic atherosclerosis and inflammation

Targeting fatty acid synthase reduces aortic atherosclerosis and inflammation

Abstract Fatty acid synthase (FAS) is predominantly expressed in the liver and adipose tissue. It plays vital roles in de novo synthesis of saturated fatty acids and regulates insulin sensitivity. We previously demonstrated that serum circulating FAS (cFAS) is a clinical biomarker for advanced ather...

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Bibliographic Details
Main Authors: Rodrigo Meade, Dina Ibrahim, Connor Engel, Larisa Belaygorod, Batool Arif, Fong-Fu Hsu, Sangeeta Adak, Ryan Catlett, Mingzhou Zhou, Ma. Xenia G. Ilagan, Clay F. Semenkovich, Mohamed A. Zayed
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07656-1

Internet

https://doi.org/10.1038/s42003-025-07656-1

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