Reorganization of Parvalbumin Immunopositive Perisomatic Innervation of Principal Cells in Focal Cortical Dysplasia Type IIB in Human Epileptic Patients

Reorganization of Parvalbumin Immunopositive Perisomatic Innervation of Principal Cells in Focal Cortical Dysplasia Type IIB in Human Epileptic Patients

Focal cortical dysplasia (FCD) is one of the most common causes of drug-resistant epilepsy. As several studies have revealed, the abnormal functioning of the perisomatic inhibitory system may play a role in the onset of seizures. Therefore, we wanted to investigate whether changes of perisomatic inh...

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Bibliographic Details
Main Authors: Cecília Szekeres-Paraczky, Péter Szocsics, Loránd Erőss, Dániel Fabó, László Mód, Zsófia Maglóczky
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
perisomatic inhibition
dysmorphic neurons
focal epilepsy
human cortex
parvalbumin
FCD
Online Access:https://www.mdpi.com/1422-0067/23/9/4746

Internet

https://www.mdpi.com/1422-0067/23/9/4746

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