Association of brain tissue cerebrospinal fluid fraction with age in healthy cognitively normal adults

Association of brain tissue cerebrospinal fluid fraction with age in healthy cognitively normal adults

Background and purposeOur objective was to apply multi-compartment T2 relaxometry in cognitively normal individuals aged 20–80 years to study the effect of aging on the parenchymal CSF fraction (CSFF), a potential measure of the subvoxel CSF space.Materials and methodsA total of 60 volunteers (age r...

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Bibliographic Details
Main Authors: Liangdong Zhou, Yi Li, Elizabeth M. Sweeney, Xiuyuan H. Wang, Amy Kuceyeski, Gloria C. Chiang, Jana Ivanidze, Yi Wang, Susan A. Gauthier, Mony J. de Leon, Thanh D. Nguyen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
T2 relaxometry
cerebrospinal fluid fraction (CSFF)
myelin water fraction (MWF)
intra/extra-cellular water fraction (IEWF)
FAST-T2
normal aging
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1162001/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2023.1162001/full

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