HPLC-Based Analysis of Impurities in Sapropterin Branded and Generic Tablets

HPLC-Based Analysis of Impurities in Sapropterin Branded and Generic Tablets

This work was aimed at the definition of a chromatographic method able to separate and quantify impurities present in sapropterin-containing drugs during an accelerated stability study. The chromatographic method was applied to the orphan drug Kuvan<sup>®</sup> and to its corresponding g...

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Bibliographic Details
Main Authors: Emanuela Scudellaro, Luciana Tartaglione, Fabio Varriale, Carmela Dell’Aversano, Orazio Taglialatela-Scafati
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
sapropterin
PKU
BH<sub>4</sub> deficiency
chemical content
impurity identification
HPLC-UV
Online Access:https://www.mdpi.com/1999-4923/12/4/323

Internet

https://www.mdpi.com/1999-4923/12/4/323

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