Dissolution Assay of Bupropion/Naltrexone Hydrochloride Salts of Bilayer Composition Tablets Following the Development and Validation of a Novel HPLC Method

Dissolution Assay of Bupropion/Naltrexone Hydrochloride Salts of Bilayer Composition Tablets Following the Development and Validation of a Novel HPLC Method

Compounded medicinal products containing bupropion hydrochloride (BUP·HCl) and naltrexone hydrochloride (NTX·HCl) are available as adjunct therapy for the management of weight in obese/overweight adults. The present work describes the development and validation of a novel RP-HPLC method for a simult...

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Bibliographic Details
Main Authors: Anna Apostolidi, Chrystalla Protopapa, Angeliki Siamidi, Marilena Vlachou, Yannis Dotsikas
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Materials
Subjects:
naltrexone
bupropion
HPLC method
experimental design
dissolution
bilayer tablets
Online Access:https://www.mdpi.com/1996-1944/15/23/8451

Internet

https://www.mdpi.com/1996-1944/15/23/8451

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