ANGPTL3 deficiency impairs lipoprotein production and produces adaptive changes in hepatic lipid metabolism

ANGPTL3 deficiency impairs lipoprotein production and produces adaptive changes in hepatic lipid metabolism

Angiopoietin-like protein 3 (ANGPTL3) is a hepatically secreted protein and therapeutic target for reducing plasma triglyceride-rich lipoproteins and low-density lipoprotein (LDL) cholesterol. Although ANGPTL3 modulates the metabolism of circulating lipoproteins, its role in triglyceride-rich lipopr...

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Bibliographic Details
Main Authors: Kendall H. Burks, Yan Xie, Michael Gildea, In-Hyuk Jung, Sandip Mukherjee, Paul Lee, Upasana Pudupakkam, Ryan Wagoner, Ved Patel, Katherine Santana, Arturo Alisio, Ira J. Goldberg, Brian N. Finck, Edward A. Fisher, Nicholas O. Davidson, Nathan O. Stitziel
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Journal of Lipid Research
Subjects:
apolipoproteins
dyslipidemias
LDL/metabolism
lipase/endothelial
PPARs
triglycerides
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227524000051

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http://www.sciencedirect.com/science/article/pii/S0022227524000051

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