Activated Protein Kinase C (PKC) Is Persistently Trafficked with Epidermal Growth Factor (EGF) Receptor

Activated Protein Kinase C (PKC) Is Persistently Trafficked with Epidermal Growth Factor (EGF) Receptor

Protein kinase Cs (PKCs) are activated by lipids in the plasma membrane and bind to a scaffold assembled on the epidermal growth factor (EGF) receptor (EGFR). Understanding how this complex is routed is important, because this determines whether EGFR is degraded, terminating signaling. Here, cells w...

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Bibliographic Details
Main Authors: Carol A. Heckman, Tania Biswas, Douglas M. Dimick, Marilyn L. Cayer
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomolecules
Subjects:
receptor tyrosine kinase
slow endocytic recycling
annexin
cortactin
vesicle trafficking
Online Access:https://www.mdpi.com/2218-273X/10/9/1288

Internet

https://www.mdpi.com/2218-273X/10/9/1288

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