Increasing Severity of Spinal Cord Injury Results in Microglia/Macrophages With Annular-Shaped Morphology and No Change in Expression of CD40 and Tumor Growth Factor-β During the Chronic Post-injury Stage

Increasing Severity of Spinal Cord Injury Results in Microglia/Macrophages With Annular-Shaped Morphology and No Change in Expression of CD40 and Tumor Growth Factor-β During the Chronic Post-injury Stage

Determination of the quantitative composition of phenotypically and morphologically different populations of resident microglia and infiltrating macrophages in spinal cord injury (SCI) of various degrees of severity could lead to much needed novel therapeutic interventions in neurotrauma. In this re...

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Bibliographic Details
Main Authors: Elvira Ruslanovna Akhmetzyanova, Anna Viktorovna Timofeeva, Davran Khudaishukurovich Sabirov, Alexander Alexandrovich Kostennikov, Alexander Alexandrovich Rogozhin, Victoria James, S. S. Arkhipova, Albert Anatolevich Rizvanov, Yana Olegovna Mukhamedshina
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
spinal cord injury
microglia
rat
polarization
morphology
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.802558/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2021.802558/full

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