Identification of a Sgo2-Dependent but Mad2-Independent Pathway Controlling Anaphase Onset in Fission Yeast

Identification of a Sgo2-Dependent but Mad2-Independent Pathway Controlling Anaphase Onset in Fission Yeast

The onset of anaphase is triggered by activation of the anaphase-promoting complex/cyclosome (APC/C) following silencing of the spindle assembly checkpoint (SAC). APC/C triggers ubiquitination of Securin and Cyclin B, which leads to loss of sister chromatid cohesion and inactivation of Cyclin B/Cdk1...

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Bibliographic Details
Main Authors: John C. Meadows, Theresa C. Lancaster, Graham J. Buttrick, Alicja M. Sochaj, Liam J. Messin, Maria del Mar Mora-Santos, Kevin G. Hardwick, Jonathan B.A. Millar
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Cell Reports
Subjects:
microtubule
kinesin
midzone
anaphase
fission yeast
spindle checkpoint
Mad2
shugoshin
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717300694

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http://www.sciencedirect.com/science/article/pii/S2211124717300694

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