Blood Pressure Control in Aging Predicts Cerebral Atrophy Related to Small-Vessel White Matter Lesions

Cerebral small-vessel damage manifests as white matter hyperintensities and cerebral atrophy on brain MRI and is associated with aging, cognitive decline and dementia. We sought to examine the interrelationship of these imaging biomarkers and the influence of hypertension in older individuals. We us...

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Bibliographic Details
Main Authors: Kyle C. Kern, Clinton B. Wright, Kaitlin L. Bergfield, Megan C. Fitzhugh, Kewei Chen, James R. Moeller, Nooshin Nabizadeh, Mitchell S. V. Elkind, Ralph L. Sacco, Yaakov Stern, Charles S. DeCarli, Gene E. Alexander
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00132/full