New Phosphorylation Sites of Rad51 by c-Met Modulates Presynaptic Filament Stability

New Phosphorylation Sites of Rad51 by c-Met Modulates Presynaptic Filament Stability

Genomic instability through deregulation of DNA repair pathways can initiate cancer and subsequently result in resistance to chemo and radiotherapy. Understanding these biological mechanisms is therefore essential to overcome cancer. RAD51 is the central protein of the Homologous Recombination (HR)...

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Bibliographic Details
Main Authors: Thomas Chabot, Alain Defontaine, Damien Marquis, Axelle Renodon-Corniere, Emmanuelle Courtois, Fabrice Fleury, Yvonnick Cheraud
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cancers
Subjects:
RAD51 recombinase
HGFR kinase
post-translational modification
DNA repair
cancer outcomes
Online Access:https://www.mdpi.com/2072-6694/11/3/413

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https://www.mdpi.com/2072-6694/11/3/413

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