Identification α-Amylase Inhibitors of <i>Vernonia amygdalina</i> Leaves Extract Using Metabolite Profiling Combined with Molecular Docking

Identification α-Amylase Inhibitors of <i>Vernonia amygdalina</i> Leaves Extract Using Metabolite Profiling Combined with Molecular Docking

Vernonia amygdalina was reported to be used as a therapy for Diabetes Mellitus (DM). One of the mechanisms of therapy DM was to inhibit the action of the α-amylase enzyme. This study aimed to prove the presence of compounds that could inhibit the action of α-amylase. Vernonia amygdalina leaves were...

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Bibliographic Details
Main Authors: Norainny Yunitasari, Tri Joko Raharjo, Respati Tri Swasono, Harno Dwi Pranowo
Format: Article
Language:English
Published: Department of Chemistry, Universitas Gadjah Mada 2022-03-01
Series:Indonesian Journal of Chemistry
Subjects:
ethyl acetate extract
diabetes mellitus
lc-hrms
protein 4gqr
molecular dynamic simulation
Online Access:https://jurnal.ugm.ac.id/ijc/article/view/71499

Internet

https://jurnal.ugm.ac.id/ijc/article/view/71499

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