Strong impact of sulfotransferases on DNA adduct formation by 4‐aminobiphenyl in bladder and liver in mice

Abstract Bladder cancer risk is 3‐4 times higher in men than women, but the reason is poorly understood. In mice, male bladder is also more susceptible than female bladder to 4‐aminobiphenyl (ABP), a major human bladder carcinogen; however, female liver is more susceptible than male liver to ABP. We...

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Bibliographic Details
Main Authors: Yun Li, Zhidan Chen, Joseph D. Paonessa, Walter Meinl, Arup Bhattacharya, Hansruedi Glatt, Paul Vouros, Yuesheng Zhang
Format: Article
Language:English
Published: Wiley 2018-11-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.1779