Cell-free DNA methylation-defined prognostic subgroups in small-cell lung cancer identified by leukocyte methylation subtraction

Cell-free DNA methylation-defined prognostic subgroups in small-cell lung cancer identified by leukocyte methylation subtraction

Summary: Small-cell lung cancer (SCLC) methylome is understudied. Here, we comprehensively profile SCLC using cell-free methylated DNA immunoprecipitation followed by sequencing (cfMeDIP-seq). Cell-free DNA (cfDNA) from plasma of 74 patients with SCLC pre-treatment and from 20 non-cancer participant...

Full description

Bibliographic Details
Main Authors: Sami Ul Haq, Sabine Schmid, Mansi K. Aparnathi, Katrina Hueniken, Luna Jia Zhan, Danielle Sacdalan, Janice J.N. Li, Nicholas Meti, Devalben Patel, Dangxiao Cheng, Vivek Philip, Ming S. Tsao, Michael Cabanero, Daniel de Carvalho, Geoffrey Liu, Scott V. Bratman, Benjamin H. Lok
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:iScience
Subjects:
Cancer
Cancer systems biology
Epigenetics
Genomics
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422201759X

Internet

http://www.sciencedirect.com/science/article/pii/S258900422201759X

Similar Items