Case Report: Systemic Treatment and Serial Genomic Sequencing of Metastatic Prostate Adenocarcinoma Progressing to Small Cell Carcinoma

Case Report: Systemic Treatment and Serial Genomic Sequencing of Metastatic Prostate Adenocarcinoma Progressing to Small Cell Carcinoma

Small cell carcinoma (SCC)/neuroendocrine prostate cancer (NEPC) is a rare and highly aggressive subtype of prostate cancer associated with an AR(androgen receptor)-null phenotype and visceral metastases. This study presents a 44-year-old man originally diagnosed with metastatic hormone-sensitive pr...

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Bibliographic Details
Main Authors: XiaoJun Lu, Wenwen Gao, Yu Zhang, Tao Wang, Hongliang Gao, Qing Chen, Xiaolei Shi, Bijun Lian, Wenhui Zhang, Xu Gao, Jing Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
neuroendocrine differentiation
small cell carcinoma
whole-exome sequencing
neuroendocrine prostate cancer
clonal evolution
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.732071/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.732071/full

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