AR mRNA stability is increased with AR-antagonist resistance via 3′UTR variants
Advanced prostate cancer is often treated with AR antagonists w hich target the androgen receptor (AR) on which the growth of the tumour depends. Prosta te cancer often develops AR-antagonist resistance via a plethora of mechanisms, many of which are as yet unknown, but it is thought that AR upregul...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Bioscientifica
2019-12-01
|
| Series: | Endocrine Connections |
| Subjects: | |
| Online Access: | https://doi.org/10.1530/EC-19-0340 |