Endogenous Fructose Metabolism Could Explain the Warburg Effect and the Protection of SGLT2 Inhibitors in Chronic Kidney Disease

Endogenous Fructose Metabolism Could Explain the Warburg Effect and the Protection of SGLT2 Inhibitors in Chronic Kidney Disease

Chronic low-grade inflammation underlies the pathogenesis of non-communicable diseases, including chronic kidney diseases (CKD). Inflammation is a biologically active process accompanied with biochemical changes involving energy, amino acid, lipid and nucleotides. Recently, glycolysis has been obser...

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Bibliographic Details
Main Authors: Takahiko Nakagawa, Laura G. Sanchez-Lozada, Ana Andres-Hernando, Hideto Kojima, Masato Kasahara, Bernardo Rodriguez-Iturbe, Petter Bjornstad, Miguel A. Lanaspa, Richard J. Johnson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
fructose
The Warburg effect
CKD - chronic kidney disease
inflammation
fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.694457/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.694457/full

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