High concentrations of H2O2 make aerobic glycolysis energetically more favourable than cellular respiration.

Since the original observation of the Warburg Effect in cancer cells, over eight decades ago, the major question of why aerobic glycolysis is favored over oxidative phosphorylation has remained unresolved. An understanding of this phenomenon may well be the key to the development of more effective c...

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Bibliographic Details
Main Authors: Hamid R Molavian, Mohammad Kohandel, Siv Sivaloganathan
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00362/full