Pharmacokinetic assessment of vancomycin in critically ill patients and nephrotoxicity prediction using individualized pharmacokinetic parameters

Pharmacokinetic assessment of vancomycin in critically ill patients and nephrotoxicity prediction using individualized pharmacokinetic parameters

Introduction: Therapeutic drug monitoring (TDM) and pharmacokinetic assessments of vancomycin would be essential to avoid vancomycin-associated nephrotoxicity and obtain optimal therapeutic and clinical responses. Different pharmacokinetic parameters, including trough concentration and area under th...

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Bibliographic Details
Main Authors: Parisa Ghasemiyeh, Afsaneh Vazin, Farid Zand, Elham Haem, Iman Karimzadeh, Amir Azadi, Mansoor Masjedi, Golnar Sabetian, Reza Nikandish, Soliman Mohammadi-Samani
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
vancomycin
therapeutic drug monitoring (TDM)
pharmacokinetic parameters
critically ill patients
nephrotoxicity
cut-off point
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.912202/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.912202/full

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