Oolong Tea Consumption and the Risk of Oral Squamous Cell Carcinoma: A Propensity Score-Based Analysis in Southeast China
Oolong tea is one of the world's most popular non-alcoholic beverages, particularly in coastal Southeast China. Hitherto, epidemiological studies on the association between oolong tea consumption and the risk of patients with oral squamous cell carcinoma (OSCC) are very limited. This study aime...
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Frontiers Media S.A.
2022-07-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2022.928840/full |
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| author | Qingrong Deng Qingrong Deng Yuying Wu Yuying Wu Xiaoying Hu Xiaoying Hu Huiqing Wu Huiqing Wu Mengzhu Guo Mengzhu Guo Yimin Lin Yimin Lin Menglin Yu Menglin Yu Wenwen Huang Wenwen Huang Yuxuan Wu Yuxuan Wu Lisong Lin Yu Qiu Jing Wang Baochang He Baochang He Baochang He Fa Chen Fa Chen |
| author_facet | Qingrong Deng Qingrong Deng Yuying Wu Yuying Wu Xiaoying Hu Xiaoying Hu Huiqing Wu Huiqing Wu Mengzhu Guo Mengzhu Guo Yimin Lin Yimin Lin Menglin Yu Menglin Yu Wenwen Huang Wenwen Huang Yuxuan Wu Yuxuan Wu Lisong Lin Yu Qiu Jing Wang Baochang He Baochang He Baochang He Fa Chen Fa Chen |
| author_sort | Qingrong Deng |
| collection | DOAJ |
| description | Oolong tea is one of the world's most popular non-alcoholic beverages, particularly in coastal Southeast China. Hitherto, epidemiological studies on the association between oolong tea consumption and the risk of patients with oral squamous cell carcinoma (OSCC) are very limited. This study aimed to evaluate the potential effect of oolong tea consumption on OSCC risk in Southeast China. From January 2010 to October 2020, face-to-face interviews were conducted for 744 newly diagnosed OSCC patients and 1,029 healthy controls to collect information on demographics, oolong tea consumption behaviors, and other lifestyle factors. Propensity score matching (PSM), inverse probability of treatment weight (IPTW), and stabilized inverse probability of treatment weight (SIPTW) were utilized to minimize confounding effects. Multivariate, conditional, and weighted logistic regression was used to evaluate the associations of oolong tea consumption behaviors with OSCC risk. Participants who drank oolong tea showed a lower risk of OSCC when compared to their non-drink counterparts [PSM population, OR (95%CI): 0.69 (0.49–0.97); SIPTW population, OR (95%CI): 0.74 (0.58–0.94)]. Moreover, the reduced risk was found to be significantly associated with certain tea-drinking habits (consumed amount over 500 mL per day, a duration of <20 years, age at initiation older than 30 years, and warm and moderately concentrated tea). Similar results were yielded in the sensitivity analyses (Multivariate adjustment and the IPTW analysis). Furthermore, subgroup analysis revealed that the negative association of oolong tea drinking with OSCC risk was more evident among those with poor oral hygiene. This study provides supportive evidence that oolong tea consumption may have a potentially beneficial effect in preventing OSCC, especially for those with poor oral hygiene. |
| first_indexed | 2024-04-13T21:24:42Z |
| format | Article |
| id | doaj.art-0be19b719bbb402586bbc443f0fcee93 |
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| language | English |
| last_indexed | 2024-04-13T21:24:42Z |
| publishDate | 2022-07-01 |
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| series | Frontiers in Nutrition |
| spelling | doaj.art-0be19b719bbb402586bbc443f0fcee932022-12-22T02:29:22ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-07-01910.3389/fnut.2022.928840928840Oolong Tea Consumption and the Risk of Oral Squamous Cell Carcinoma: A Propensity Score-Based Analysis in Southeast ChinaQingrong Deng0Qingrong Deng1Yuying Wu2Yuying Wu3Xiaoying Hu4Xiaoying Hu5Huiqing Wu6Huiqing Wu7Mengzhu Guo8Mengzhu Guo9Yimin Lin10Yimin Lin11Menglin Yu12Menglin Yu13Wenwen Huang14Wenwen Huang15Yuxuan Wu16Yuxuan Wu17Lisong Lin18Yu Qiu19Jing Wang20Baochang He21Baochang He22Baochang He23Fa Chen24Fa Chen25Department of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, ChinaKey Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, ChinaKey Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, ChinaKey Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, ChinaKey Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, ChinaKey Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, ChinaKey Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, ChinaKey Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, ChinaKey Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, ChinaKey Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaDepartment of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, ChinaDepartment of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, ChinaLaboratory Center, The Major Subject of Environment and Health of Fujian Key Universities, School of Public Health, Fujian Medical University, Fuzhou, ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, ChinaKey Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaDepartment of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, ChinaKey Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaOolong tea is one of the world's most popular non-alcoholic beverages, particularly in coastal Southeast China. Hitherto, epidemiological studies on the association between oolong tea consumption and the risk of patients with oral squamous cell carcinoma (OSCC) are very limited. This study aimed to evaluate the potential effect of oolong tea consumption on OSCC risk in Southeast China. From January 2010 to October 2020, face-to-face interviews were conducted for 744 newly diagnosed OSCC patients and 1,029 healthy controls to collect information on demographics, oolong tea consumption behaviors, and other lifestyle factors. Propensity score matching (PSM), inverse probability of treatment weight (IPTW), and stabilized inverse probability of treatment weight (SIPTW) were utilized to minimize confounding effects. Multivariate, conditional, and weighted logistic regression was used to evaluate the associations of oolong tea consumption behaviors with OSCC risk. Participants who drank oolong tea showed a lower risk of OSCC when compared to their non-drink counterparts [PSM population, OR (95%CI): 0.69 (0.49–0.97); SIPTW population, OR (95%CI): 0.74 (0.58–0.94)]. Moreover, the reduced risk was found to be significantly associated with certain tea-drinking habits (consumed amount over 500 mL per day, a duration of <20 years, age at initiation older than 30 years, and warm and moderately concentrated tea). Similar results were yielded in the sensitivity analyses (Multivariate adjustment and the IPTW analysis). Furthermore, subgroup analysis revealed that the negative association of oolong tea drinking with OSCC risk was more evident among those with poor oral hygiene. This study provides supportive evidence that oolong tea consumption may have a potentially beneficial effect in preventing OSCC, especially for those with poor oral hygiene.https://www.frontiersin.org/articles/10.3389/fnut.2022.928840/fulloolong tea consumptionOSCCpropensity score analysesoral hygienerisk assessment |
| spellingShingle | Qingrong Deng Qingrong Deng Yuying Wu Yuying Wu Xiaoying Hu Xiaoying Hu Huiqing Wu Huiqing Wu Mengzhu Guo Mengzhu Guo Yimin Lin Yimin Lin Menglin Yu Menglin Yu Wenwen Huang Wenwen Huang Yuxuan Wu Yuxuan Wu Lisong Lin Yu Qiu Jing Wang Baochang He Baochang He Baochang He Fa Chen Fa Chen Oolong Tea Consumption and the Risk of Oral Squamous Cell Carcinoma: A Propensity Score-Based Analysis in Southeast China Frontiers in Nutrition oolong tea consumption OSCC propensity score analyses oral hygiene risk assessment |
| title | Oolong Tea Consumption and the Risk of Oral Squamous Cell Carcinoma: A Propensity Score-Based Analysis in Southeast China |
| title_full | Oolong Tea Consumption and the Risk of Oral Squamous Cell Carcinoma: A Propensity Score-Based Analysis in Southeast China |
| title_fullStr | Oolong Tea Consumption and the Risk of Oral Squamous Cell Carcinoma: A Propensity Score-Based Analysis in Southeast China |
| title_full_unstemmed | Oolong Tea Consumption and the Risk of Oral Squamous Cell Carcinoma: A Propensity Score-Based Analysis in Southeast China |
| title_short | Oolong Tea Consumption and the Risk of Oral Squamous Cell Carcinoma: A Propensity Score-Based Analysis in Southeast China |
| title_sort | oolong tea consumption and the risk of oral squamous cell carcinoma a propensity score based analysis in southeast china |
| topic | oolong tea consumption OSCC propensity score analyses oral hygiene risk assessment |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2022.928840/full |
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