Genetic diversity modulates the physical and transcriptomic response of skeletal muscle to simulated microgravity in male mice

Abstract Developments in long-term space exploration necessitate advancements in countermeasures against microgravity-induced skeletal muscle loss. Astronaut data shows considerable variation in muscle loss in response to microgravity. Previous experiments suggest that genetic background influences...

Full description

Bibliographic Details
Main Authors: Yasmina Zeineddine, Michael A. Friedman, Evan G. Buettmann, Lovell B. Abraham, Gabriel A. Hoppock, Henry J. Donahue
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:npj Microgravity
Online Access:https://doi.org/10.1038/s41526-023-00334-8