Low number of neurosecretory vesicles in neuroblastoma impairs massive catecholamine release and prevents hypertension

Low number of neurosecretory vesicles in neuroblastoma impairs massive catecholamine release and prevents hypertension

IntroductionNeuroblastoma (NB) is a pediatric cancer of the developing sympathetic nervous system. It produces and releases metanephrines, which are used as biomarkers for diagnosis in plasma and urine. However, plasma catecholamine concentrations remain generally normal in children with NB. Thus, u...

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Bibliographic Details
Main Authors: Annick Mühlethaler-Mottet, Silvia Uccella, Deborah Marchiori, Stefano La Rosa, Jean Daraspe, Katia Balmas Bourloud, Maja Beck Popovic, Philippe J. Eugster, Eric Grouzmann, Karim Abid
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Endocrinology
Subjects:
neuroblastoma
pheochromocytoma
catecholamine
metanephrine
biomarkers
neurosecretory vesicles
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1027856/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.1027856/full

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