RABL6A Promotes Pancreatic Neuroendocrine Tumor Angiogenesis and Progression In Vivo

RABL6A Promotes Pancreatic Neuroendocrine Tumor Angiogenesis and Progression In Vivo

Pancreatic neuroendocrine tumors (pNETs) are difficult-to-treat neoplasms whose incidence is rising. Greater understanding of pNET pathogenesis is needed to identify new biomarkers and targets for improved therapy. RABL6A, a novel oncogenic GTPase, is highly expressed in patient pNETs and required f...

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Bibliographic Details
Main Authors: Chandra K. Maharjan, Shaikamjad Umesalma, Courtney A. Kaemmer, Viviane P. Muniz, Casey Bauchle, Sarah L. Mott, K. D. Zamba, Patrick Breheny, Mariah R. Leidinger, Benjamin W. Darbro, Samuel B. Stephens, David K. Meyerholz, Dawn E. Quelle
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomedicines
Subjects:
pancreatic neuroendocrine tumors
RIP-Tag2 mouse model
RABL6A
angiogenesis
<i>c-Myc</i>
Online Access:https://www.mdpi.com/2227-9059/9/6/633

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https://www.mdpi.com/2227-9059/9/6/633

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