ATG4B and pS383/392-ATG4B serve as potential biomarkers and therapeutic targets of colorectal cancer

Abstract Background Autophagy related protease 4B (ATG4B) is a protease required for autophagy processing, which is strongly implicated in cancer progression.  Phosphorylation of ATG4B is crucial for activation of its protease activity.  However, little is known about the relationship of ATG4B and i...

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Main Authors: Wan-Hsiang Hu, Ting-Ting Liu, Pei-Feng Liu, Paul Morgan, I-Ling Lin, Wei-Lun Tsai, Yi-Yun Cheng, Ang-Tsen Hsieh, Tsung-Hui Hu, Chih-Wen Shu
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-023-02909-7