Potentiation of gamma aminobutyric acid receptors (GABAAR) by Ethanol: How are inhibitory receptors affected?

In recent years there has been an increase in the understanding of ethanol actions on the type A -aminobutyric acid chloride channel (GABAAR), a member of the pentameric ligand gated ion channels (pLGICs). However, the mechanism by which ethanol potentiates the complex is still not fully understood...

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Bibliographic Details
Main Authors: Benjamin eFörstera, P A Castro, Gustavo eMoraga-Cid, Luis Gerardo Aguayo
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00114/full