Inhibition of DAI refrains dendritic cells from maturation and prolongs murine islet and skin allograft survival
IntroductionCentral to allograft rejection is the T cell-mediated adaptive immune response initiated by activated dendritic cells (DCs). Previous studies have shown that the DNA-dependent activator of IFN regulatory factors (DAI) is involved in the maturation and activation of DCs. Therefore, we hy...
Main Authors: | Pengrui Cheng, Qian Jian, Zongli Fu, Ronghai Deng, Yi Ma |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-05-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1182851/full |
Similar Items
-
Dysregulation of innate cell types in the hepatic immune microenvironment of alcoholic liver cirrhosis
by: Ao Ren, et al.
Published: (2023-02-01) -
A unique profile of insulin antibody titer in islet‐transplanted patients
by: Yamato Keidai, et al.
Published: (2022-11-01) -
Engineering strategies of islet products for endocrine regeneration
by: Yue Cheng, et al.
Published: (2023-06-01) -
The Current Status of Allogenic Islet Cell Transplantation
by: Zofia Czarnecka, et al.
Published: (2023-10-01) -
Islets-on-Chip: A Tool for Real-Time Assessment of Islet Function Prior to Transplantation
by: Matthieu Raoux, et al.
Published: (2023-10-01)