Preclinical studies of safety, immunogenicity and protective activity of attenuated Bordetella pertussis bacteria on the Macaca mulatta model

Preclinical studies of safety, immunogenicity and protective activity of attenuated Bordetella pertussis bacteria on the Macaca mulatta model

Introduction. An increasing incidence of pertussis among different groups of population and shortcomings of the existing preventive solutions pinpoint urgency of development of new safe vaccines suitable for immunization of infants and for booster immunization of adolescents and adults.The purpose o...

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Bibliographic Details
Main Authors: Alisa Yu. Medkova, Lyudmila N. Sinyashina, Astanda A. Amichba, Evgeniy G. Semin, Zinaida V. Shevtsova, Alisa Z. Matua, Anush A. Djidaryan, Dzhenni T. Kubrava, Irina G. Kondzhariya, Vladimir S. Barkaya, Zurab Ya. Mikvabiya, Gennadiy I. Karataev
Format: Article
Language:Russian
Published: Central Research Institute for Epidemiology 2020-09-01
Series:Журнал микробиологии, эпидемиологии и иммунобиологии
Subjects:
pertussis
live intranasal vaccine
protective activity
attenuated bordetella pertussis bacteria
nonhuman primates
Online Access:https://microbiol.elpub.ru/jour/article/view/868

Internet

https://microbiol.elpub.ru/jour/article/view/868

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