ROMA: representation and quantification of module activity from target expression data

ROMA: representation and quantification of module activity from target expression data

In many analysis of high-throughput data in systems biology, there is a need to quantify the activity of a set of genes in individual samples. A typical example is the case where it is necessary to estimate the activity of a transcription factor (which is often not directly measurable) from the expr...

Full description

Bibliographic Details
Main Authors: Loredana eMartignetti, Laurence eCalzone, Eric eBonnet, Emmanuel eBARILLOT, Andrei eZinovyev
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Genetics
Subjects:
Gene Expression
Proteomics
Transcription Factors
Gene set
Module Activity
Overdispersed pathway
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00018/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00018/full

Similar Items