Ouabain enhances ADPKD cell apoptosis via the intrinsic pathway

Progression of autosomal dominant polycystic kidney disease (ADPKD) is highly influenced by factors circulating in blood. We have shown that the hormone ouabain enhances several characteristics of the ADPKD cystic phenotype, including the rate of cell proliferation, fluid secretion and the capacity...

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Bibliographic Details
Main Authors: Gustavo eBlanco, Jessica eVenugopal
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00107/full