Metal-enriched HSP90 nanoinhibitor overcomes heat resistance in hyperthermic intraperitoneal chemotherapy used for peritoneal metastases

Metal-enriched HSP90 nanoinhibitor overcomes heat resistance in hyperthermic intraperitoneal chemotherapy used for peritoneal metastases

Abstract Clinical hyperthermic intraperitoneal chemotherapy (HIPEC) is regarded as a potential treatment that can prolong survival of patients with peritoneal metastases after cytoreductive surgery. However, treated tumor cells are prone to becoming heat resistant to HIPEC therapy through high expre...

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Bibliographic Details
Main Authors: Qiang Wang, Peng Liu, Yingfei Wen, Kuan Li, Bo Bi, Bin-bin Li, Miaojuan Qiu, Shiqiang Zhang, You Li, Jia Li, Hengxing Chen, Yuan Yin, Leli Zeng, Changhua Zhang, Yulong He, Jing Zhao
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Molecular Cancer
Subjects:
Heat shock protein 90 inhibitor
Epigallocatechin gallate
Heat stress resistance
Pyroptosis
Hyperthermic intraperitoneal chemotherapy
Online Access:https://doi.org/10.1186/s12943-023-01790-2

Internet

https://doi.org/10.1186/s12943-023-01790-2

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