Liver epithelial focal adhesion kinase modulates fibrogenesis and hedgehog signaling
Focal adhesion kinase (FAK) is an important mediator of extracellular matrix–integrin mechano-signal transduction that regulates cell motility, survival, and proliferation. As such, FAK is being investigated as a potential therapeutic target for malignant and fibrotic diseases, and numerous clinical...
Glavni autori: | , , , , , , , , |
---|---|
Format: | Članak |
Jezik: | English |
Izdano: |
American Society for Clinical investigation
2020-10-01
|
Serija: | JCI Insight |
Teme: | |
Online pristup: | https://doi.org/10.1172/jci.insight.141217 |