Liver epithelial focal adhesion kinase modulates fibrogenesis and hedgehog signaling
Focal adhesion kinase (FAK) is an important mediator of extracellular matrix–integrin mechano-signal transduction that regulates cell motility, survival, and proliferation. As such, FAK is being investigated as a potential therapeutic target for malignant and fibrotic diseases, and numerous clinical...
| मुख्य लेखकों: | , , , , , , , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
American Society for Clinical investigation
2020-10-01
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| श्रृंखला: | JCI Insight |
| विषय: | |
| ऑनलाइन पहुंच: | https://doi.org/10.1172/jci.insight.141217 |