Salinomycin inhibits epigenetic modulator EZH2 to enhance death receptors in colon cancer stem cells

Salinomycin inhibits epigenetic modulator EZH2 to enhance death receptors in colon cancer stem cells

Drug resistance is one of the trademark features of Cancer Stem Cells (CSCs). We and others have recently shown that paucity of functional death receptors (DR4/5) on the cell surface of tumour cells is one of the major reasons for drug resistance, but their involvement in the context of in CSCs is p...

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Bibliographic Details
Main Authors: Anup Kumar Singh, Ayushi Verma, Akhilesh Singh, Rakesh Kumar Arya, Shrankhla Maheshwari, Priyank Chaturvedi, Mushtaq Ahmad Nengroo, Krishan Kumar Saini, Achchhe Lal Vishwakarma, Kavita Singh, Jayanta Sarkar, Dipak Datta
Format: Article
Language:English
Published: Taylor & Francis Group 2021-02-01
Series:Epigenetics
Subjects:
ezh2
cancer stem cells
death receptors
salinomycin
apoptosis
Online Access:http://dx.doi.org/10.1080/15592294.2020.1789270

Internet

http://dx.doi.org/10.1080/15592294.2020.1789270

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