Selecting short length nucleic acids localized in exosomes improves plasma EGFR mutation detection in NSCLC patients

Selecting short length nucleic acids localized in exosomes improves plasma EGFR mutation detection in NSCLC patients

Abstract Background Exosomal nucleic acid (exoNA) is a feasible target to improve the sensitivity of EGFR mutation testing in non-small cell lung cancer patients with limited cell-free DNA (cfDNA) mutant copies. However, the type and size of target exoNA related to the sensitivity of EGFR mutation t...

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Bibliographic Details
Main Authors: Yoonjung Kim, Saeam Shin, Boyeon Kim, Kyung-A Lee
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Cancer Cell International
Subjects:
Liquid biopsy
Extracellular vesicles
Circulating tumor DNA
Non-small cell lung cancer
Epidermal growth factor receptor
ddPCR
Online Access:http://link.springer.com/article/10.1186/s12935-019-0978-8

Internet

http://link.springer.com/article/10.1186/s12935-019-0978-8

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