FKBP39 controls nutrient dependent Nprl3 expression and TORC1 activity in Drosophila

FKBP39 controls nutrient dependent Nprl3 expression and TORC1 activity in Drosophila

Abstract Target of Rapamycin Complex 1 (TORC1) is a master regulator that coordinates nutrient status with cell metabolism. The GTPase-activating protein towards Rags complex 1 (GATOR1) inhibits TORC1 activity and protects cells from damage during periods of stress. Here we characterize multiple pat...

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Bibliographic Details
Main Authors: Ying Zhou, Jian Guo, Xinyu Wang, Yang Cheng, Jianwen Guan, Priyam Barman, Ming-An Sun, Yuanyuan Fu, Wanhong Wei, Congjing Feng, Mary A. Lilly, Youheng Wei
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03860-z

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https://doi.org/10.1038/s41419-021-03860-z

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